EGFR/Cytokine-IN-1

SKU: orb3173853

Description

EGFR/Cytokine-IN-1 is an inhibitor targeting EGFR with an IC50 of 0.03 μM, as well as cytokines TNF-α (IC50= 3.1 μM) and IL-6 (IC50= 1.6 μM). This compound demonstrates significant anticancer activity against both A549 and MCF7 cell lines. It effectively reduces IL-6 and TNF-α levels in A549 cells and exhibits favorable ADMET properties. EGFR/Cytokine-IN-1 is capable of inducing apoptosis in a dose-dependent manner and is applicable in breast and lung cancer research.

Research Area

Cardiovascular Research, Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• Target: Apoptosis,Interleukin,EGFR,TNF

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Apoptosis,Interleukin,EGFR,TNF