EGFR/CDK2-IN-4

SKU: orb2277729

Description

EGFR/CDK2-IN-4 (compound 4c) is a dual inhibitor targeting EGFR and CDK-2, with IC50 values of 89.6 nM for EGFR and 165.4 nM for CDK-2. It induces apoptosis and S phase cell cycle arrest in MCF-7 cells, showing significant anti-cancer activity with an IC50 of 2.74 μM against MCF-7 cells.

Key Properties

• MW: 468.55
• Formula: C₂₄H₁₆N₆OS₂
• Target: CDK,EGFR

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

CDK,EGFR