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EGFR/CDK2-IN-4

SKU: orb2277729

Description

EGFR/CDK2-IN-4 is a dual-targeting inhibitor with IC50 values of 89.6 nM for EGFR and 165.4 nM for CDK2. It exhibits anti-proliferative activity in MCF-7 breast cancer cells (IC50 = 2.74 µM) by inducing S-phase cell cycle arrest and apoptosis, making it a useful tool for oncology research in vitro.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

Key Properties

MW468.55
FormulaC24H16N6OS2
TargetEGFR,CDK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

EGFR/CDK2-IN-4 (orb2277729)

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