EGFR/CDK2-IN-2

SKU: orb2277731

Description

EGFR/CDK2-IN-2 is a potent dual inhibitor of EGFR (IC50 = 19.6 nM) and CDK2 (IC50 = 87.9 nM). It demonstrates anticancer activity by inducing apoptosis and S-phase cell cycle arrest in MCF-7 breast cancer cells, with a cellular IC50 of 0.39 µM, making it a useful research tool for oncology and kinase signaling studies.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin; Cell Biology, Signal Transduction

Key Properties

• MW: 884.99
• Formula: C₄₉H₃₂N₁₂O₂S₂
• Target: EGFR,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR,CDK