EGFR/BRAFV600E-IN-1

SKU: orb1687541

Description

EGFR/BRAFV600E-IN-1 (Compound 23) is a dual inhibitor of EGFR and BRAFV600E with IC50 values of 0.08 μM and 0.15 μM, respectively. It demonstrates anti-proliferative activity in various cancer cell lines, including A-549, MCF-7, Panc-1, and HT-29. This compound is a valuable research tool for investigating oncogenic signaling and potential therapeutic strategies in vitro.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2492429-45-3
• MW: 437.92
• Formula: C₂₄H₂₄ClN₃O₃
• SMILES: O=C1N2C(=C(C)C=3C2=CC=C(Cl)C3)C(=O)N(CCC4=CC=C(C=C4)N5CCOCC5)C1
• Target: Raf,EGFR,Apoptosis,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

164517079