EGFR/AURKB-IN-1

SKU: orb2566334

Description

EGFR/AURKB-IN-1 is a potent dual inhibitor of EGFR(L858R) and AURKB with IC50 values of 0.07 and 1.1, respectively. It suppresses cancer cell proliferation and metastasis by targeting key hydrophobic pockets, making it a valuable tool for in vitro and in vivo oncology research, particularly in studying non-small cell lung cancer mechanisms.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 3008543-34-5
• MW: 396.44
• Formula: C₂₃H₂₀N₆O
• SMILES: N(C1=C2C(NC(=C2)C=3N(C)N=CC3)=NC=N1)C4=CC=C(OCC5=CC=CC=C5)C=C4
• Target: EGFR,Aurora Kinase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

170385357