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EGFR WT/T790M-IN-3

SKU: orb3136682

Description

EGFRWT/T790M-IN-3 is an irreversible, covalent inhibitor of EGFRWT and EGFRT790M with IC50 values of 28.1 nM and 24.6 nM, respectively. It also inhibits tubulin polymerization, exhibiting an IC50 of 5.1 μM. EGFRWT/T790M-IN-3 demonstrates significant antiproliferative effects on HCT116 and T47D cells, with IC50 values of 3.12 μM and 4.12 μM, respectively. This compound is applicable in research pertaining to cancers such as non-small cell lung cancer, colon cancer, and breast cancer.

Research Area

Cell Biology

Images & Validation

Key Properties

TargetMicrotubule Associated,EGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

EGFR WT/T790M-IN-3 (orb3136682)

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