EGFR T790M/L858R-IN-6

SKU: orb2566337

Description

EGFR T790M/L858R-IN-6 (compound 53) is a potent pyrimidine-based inhibitor of the EGFR T790M/L858R mutant, showing 90.88% enzyme inhibition at 0.05 µM. It is a valuable research tool for studying resistant non-small cell lung cancer (NSCLC) in biochemical and cellular assays.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	3032760-71-4
MW	481.55
Formula	C₂₇H₂₇N₇O₂
SMILES	CN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(NCCO)C(NC5=CC=CC=N5)=C4)=NC=C3
Target	EGFR

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

171103779 ↗

Key Properties

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No computed properties available.

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