EGFR T790M/L858R-IN-5

SKU: orb2566338

Description

EGFR T790M/L858R-IN-5 (Example 52) is a highly effective small molecule inhibitor, showing 92.9% inhibition of the EGFR T790M/L858R mutant at 50 nM. This compound is a valuable research tool for studying resistant non-small cell lung cancer (NSCLC) in both biochemical and cellular assays.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 3032760-70-3
• MW: 509.61
• Formula: C₂₈H₃₁N₉O
• SMILES: CN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(NCCN(C)C)C(NC=5C=CN=CN5)=C4)=NC=C3
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171391413