EGFR-IN-81

SKU: orb2278030

Description

EGFR-IN-81 is a potent small molecule inhibitor of both wild-type EGFR and the L858R/T790M mutant, with IC50 values in the low nanomolar range. It also demonstrates cytotoxic activity against MCF-7 and HCT116 cancer cell lines in vitro, making it a useful research tool for studying EGFR-driven oncogenesis and resistance mechanisms.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• MW: 551.52
• Formula: C₂₈H₂₄F₃N₅O₄
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR