EGFR-IN-74

SKU: orb1744383

Description

EGFR-IN-74 is a potent small molecule inhibitor selectively targeting EGFR L858R/T790M mutations with an IC50 of 138 nM. It induces apoptosis in cancer cells and is a valuable tool for in vitro and in vivo studies of resistant non-small cell lung cancer.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• MW: 729.57
• Formula: C₃₂H₂₈BrF₃N₆O₄S
• SMILES: CCOC(=O)C1=C(C2=C(C=CC(=C2)Br)N=C1N3C=CN=C3)N4CCN(CC4)C5=CC=CC=C5NS(=O)(=O)C6=CC=C(C=C6)C(F)(F)F
• Target: EGFR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166177024