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EGFR-IN-73

SKU: orb1744386

Description

EGFR-IN-73 (Compound 3f) is a potent and selective inhibitor of the oncogenic EGFR Del19 mutation, demonstrating an IC50 of 119 nM. This small molecule is a valuable chemical probe for in vitro biochemical and cellular research targeting non-small cell lung cancer (NSCLC) driven by this prevalent EGFR alteration.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

CAS Number2857033-34-0
MW405.81
FormulaC19H17ClFN3O4
SMILESCOC1=C2C=C3C(=C1)N=CN=C3NC4=CC(=C(C=C4OCCOCCO2)F)Cl
TargetEGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

EGFR-IN-73 (orb1744386)

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