EGFR-IN-70

SKU: orb1744392

Description

EGFR-IN-70 is a potent and selective EGFR inhibitor, demonstrating anti-proliferative activity in vitro by suppressing EGFR phosphorylation. It shows greater potency against the EGFR L858R/T790M/C797S mutant (IC50 = 23.6 nM) than wild-type EGFR (IC50 = 307.5 nM), making it a useful compound for oncology research, including studies of resistant cancer models.

Research Area

Cell Biology

Key Properties

• MW: 626.17
• Formula: C₃₁H₃₆ClN₅O₅S
• SMILES: CCS(=O)(=O)N1C=C2C3=C1C=C(C=C3)OCCCCCCOC4=C(C=C(C(=C4)NC5=NC=C(C2=N5)Cl)C)N6CCOCC6
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

164887498