EGFR-IN-50

SKU: orb1686044

Description

EGFR-IN-50 is a potent small molecule inhibitor targeting EGFR resistance mutations, including L858R and T790M/L858R, with GI50 values of 8 nM and 6.03 μM in respective BaF3 cell models. It is a valuable research tool for studying non-small cell lung cancer (NSCLC) resistance mechanisms and evaluating anti-proliferative effects in vitro.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2044508-48-5
• MW: 564.51
• Formula: C₂₄H₂₆BrN₃O₄S₂
• SMILES: N(C=1C2=C(C=C(OCCCOC(CCSSCC=C)=O)C(OC)=C2)N=CN1)C3=CC(Br)=CC=C3
• Target: EGFR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162663118