EGFR-IN-47

SKU: orb1686855

Description

EGFR-IN-47 is a potent, orally bioavailable inhibitor targeting the EGFRL858R/T790M/C797S mutant with an IC50 of 0.01 µM. It demonstrates anti-tumor activity by inducing cell cycle arrest and apoptosis in vitro, supporting its investigation for non-small cell lung cancer (NSCLC) in preclinical research.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 3034649-73-2
• MW: 481.64
• Purity: 98.78% (May vary between batches)
• Formula: C₂₉H₃₅N₇
• SMILES: N1=CC=2C=C(N(C2N=C1NC3=CC=C(C=C3)N4CCN(C)CC4)C5CCCC5)CNC=6C=CC=CC6
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR