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Catalog Number | orb1982922 |
---|---|
Category | Small Molecules |
Description | EGFR-IN-43 (Compound 17c) is a highly effective EGFR inhibitor with single-digit nanomolar activity, uniquely combining tamoxifen or endoxifen with the EGFR inhibitor gefitinib through a covalent bond, maintaining both ER antagonist activity and EGFR inhibition capabilities, demonstrating exceptional anti-cancer efficacy [1]. |
Purity | 98.00% |
MW | 860.45 |
Formula | C50H55ClFN5O5 |
Biological Activity | EGFR-IN-43 (Compound 17c) is a highly effective EGFR inhibitor, exhibiting activity in the single-digit nanomolar range. It uniquely combines tamoxifen or endoxifen with the EGFR inhibitor gefitinib through a covalent bond, maintaining both ER antagonist activity and EGFR inhibition capabilities. This compound demonstrates exceptional anti-cancer efficacy [1]. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |