EGFR-IN-43

SKU: orb1982922

Description

EGFR-IN-43 (Compound 17c) is a potent dual-action inhibitor, covalently linking gefitinib with tamoxifen/endoxifen to simultaneously target EGFR and the estrogen receptor. It exhibits single-digit nanomolar EGFR inhibition and retains ER antagonism, demonstrating promising anti-cancer activity in cellular studies for researching combination therapies in resistant cancers.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• MW: 860.45
• Formula: C₅₀H₅₅ClFN₅O₅
• Target: Others,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others,EGFR