EGFR-IN-43

• Catalog Number: orb1982922
• Category: Small Molecules
• Description: EGFR-IN-43 (Compound 17c) is a highly effective EGFR inhibitor with single-digit nanomolar activity, uniquely combining tamoxifen or endoxifen with the EGFR inhibitor gefitinib through a covalent bond, maintaining both ER antagonist activity and EGFR inhibition capabilities, demonstrating exceptional anti-cancer efficacy [1].
• Purity: 98.00%
• MW: 860.45
• Biological Activity: EGFR-IN-43 (Compound 17c) is a highly effective EGFR inhibitor, exhibiting activity in the single-digit nanomolar range. It uniquely combines tamoxifen or endoxifen with the EGFR inhibitor gefitinib through a covalent bond, maintaining both ER antagonist activity and EGFR inhibition capabilities. This compound demonstrates exceptional anti-cancer efficacy [1].
• Formula: C₅₀H₅₅ClFN₅O₅
• Storage: -20°C
• Note: For research use only