EGFR-IN-42

• Catalog Number: orb1982923
• Category: Small Molecules
• Description: EGFR-IN-42 (Compound 17b), a potent EGFR inhibitor, demonstrates single-digit nanomolar activity by covalently linking tamoxifen or endoxifen with gefitinib, retaining both ER antagonist activity and EGFR inhibition, resulting in superior anti-cancer activity [1].
• Purity: 98.00%
• MW: 846.43
• Biological Activity: EGFR-IN-42 (Compound 17b), a potent EGFR inhibitor, demonstrates single-digit nanomolar activity by covalently linking tamoxifen or endoxifen with gefitinib, retaining both ER antagonist activity and EGFR inhibition, resulting in superior anti-cancer activity [1].
• Formula: C₄₉H₅₃ClFN₅O₅
• Storage: -20°C
• Note: For research use only