EGFR-IN-25

SKU: orb1744432

Description

EGFR-IN-25 is a potent and selective EGFR inhibitor, exhibiting an IC50 of 9 nM against BaF3 cells harboring the EGFR DEL19/T790M/C797S triple mutation and 60 nM against wild-type EGFR in A431 cells. This small molecule is a valuable research tool for investigating resistance mechanisms in non-small cell lung cancer (NSCLC) and for conducting in vitro efficacy studies.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2749562-63-6
• MW: 609.76
• Formula: C₃₄H₄₃N₉O₂
• SMILES: N(C=1C(=NC(C(N)=O)=C(NC2=CC=C(C=C2)N3CCC(CC3)N4CCN(C)CC4)N1)C5=C6C(NC=C6)=CC=C5)C7CCOCC7
• Target: Others,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163196258