EGFR-IN-22

SKU: orb1983117

Description

EGFR-IN-22 is a potent small molecule inhibitor effective against both wild-type EGFR and the triple mutant EGFR L858R/T790M/C797S, with respective IC50 values of 4.91 nM and 0.54 nM. It serves as a valuable research tool for investigating resistance mechanisms and evaluating therapeutic strategies in preclinical in vitro and in vivo models of non-small cell lung cancer.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2634646-14-1
• MW: 805.72
• Formula: C₃₈H₄₇BrFN₁₀O₂P
• SMILES: COc1cc(N2CCC3(CC2)CCN(CC3)C(C)(C)CF)c(cc1Nc1ncc(Br)c(Nc2ccc3nccnc3c2P(C)(C)=O)n1)-c1cnn(C)c1
• Target: EGFR,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156695922