EGFR-IN-204

SKU: orb3211270

Description

EGFR-IN-204 (Example 1) is a selective inhibitor targeting HER2 exon 20 mutations, with a preference for wild-type EGFR. It exhibits antiproliferative effects on cells dependent on the HER2 exon 20 YVMA insertion mutation and wild-type HER2, showing greater selectivity compared to cells dependent on wild-type EGFR. EGFR-IN-204 is applicable in non-small cell lung cancer research.

Key Properties

• CAS Number: 2989904-86-9
• MW: 565.60
• Formula: C₃₁H₂₈FN₇O₃
• SMILES: C(C=C)(=O)N1[C@]2(C[C@H](OC3=CC=4C(NC5=C(F)C(C)=C(OC6=CC=7N(C=C6)N=CN7)C=C5)=NC=NC4C=C3)C[C@@]1(CC2)[H])[H]
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR