EGFR-IN-196

SKU: orb3210258

Description

EGFR-IN-196 is an EGFR inhibitor with an IC50 of 105.96 nM. It reduces EGFR enzyme activity, lowers phosphorylated PI3K levels, and inhibits the downstream EGFR-AKT signaling pathway. EGFR-IN-196 also increases intracellular reactive oxygen species (ROS) production, induces mitochondrial depolarization, and triggers apoptosis in cancer cells. This compound is applicable in lung cancer research.

Key Properties

• Target: PI3K,Mitochondrial Metabolism,Akt,ROS,EGFR,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PI3K,Mitochondrial Metabolism,Akt,ROS,EGFR,Apoptosis