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EGFR-IN-170

SKU: orb3173299

Description

EGFR-IN-170 (Compound 5c) is an EGFR inhibitor with an IC50 of 5.17 μM. It induces apoptosis by inhibiting Bcl2 and activating Bax expression, notably increasing the Bax/Bcl2 ratio. EGFR-IN-170 exhibits potent anticancer activity and is capable of inhibiting the growth of resistant lung cancer cells.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

Key Properties

TargetBcl-2 Family,EGFR,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information