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EGFR-IN-163

SKU: orb3135484

Description

EGFR-IN-163 (Compound 13) is a competitive inhibitor of the epidermal growth factor receptor (EGFR) with an IC50 of 0.079 μM and selective inhibition on HER-2. It induces apoptosis in tumor cells and causes cell cycle arrest at the G₂/M phase. EGFR-IN-163 shows promise for investigating estrogen receptor-positive (ER+) breast cancer.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

Key Properties

TargetEGFR,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information