EGFR-IN-158

SKU: orb3027542

Description

EGFR-IN-158 (compound 12e) is an orally active EGFR inhibitor with an IC50 value of 0.22 nM for EGFR (Del19/T790M). By binding to EGFR, EGFR-IN-158 inhibits phosphorylation and downstream signaling, thereby suppressing the proliferation of tumor cell lines and promoting apoptosis.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• Formula: C₂₇H₃₅ClN₈O₄S
• Target: EGFR,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR,Apoptosis