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EGFR-IN-138

SKU: orb2814229

Description

EGFR-IN-138 (compound 19) is a potent, small-molecule EGFR inhibitor demonstrating high potency against wild-type (IC50=37 nM), L858R mutant (IC50=2.6 nM), and T790M mutant (IC50=1.9 nM) kinases. This tool compound is suitable for in vitro biochemical and cellular assays in oncology research, particularly for studying resistance mechanisms in non-small cell lung cancer models.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

MW719.79
FormulaC42H37N7O5
TargetEGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

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Protocol Information

EGFR-IN-138 (orb2814229)

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