Cart summary

You have no items in your shopping cart.

EGFR-IN-135

SKU: orb2802483

Description

EGFR-IN-135 (compound 3d) is a potent small molecule EGFR inhibitor with an IC50 of 86 nM. It demonstrates anti-proliferative activity in breast cancer cell models by inducing S-phase cell cycle arrest, supporting its use in oncology research for studying EGFR-driven signaling pathways in vitro.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

Key Properties

MW294.4
FormulaC12H14N4OS2
SMILESCC1=C(C2=NN=C(SCC(C)C)O2)N3C(SC=C3)=N1
TargetEGFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

EGFR-IN-135 (orb2802483)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%