EGFR-IN-113

SKU: orb3174999

Description

EGFR-IN-113 (compound II-1) is an EGFR kinase inhibitor with an IC50 of 14.79 μM. It induces apoptosis and inhibits cell proliferation by downregulating the Akt and Erk1/2 signaling pathways. EGFR-IN-113 is applicable in research on EGFR-driven cancers, such as lung cancer, pancreatic cancer, and breast cancer.

Key Properties

• CAS Number: 2549192-10-9
• MW: 627.07
• Formula: C₃₁H₃₂ClFN₄O₇
• SMILES: O=C(OCCCOC1=CC2=NC=NC(NC3=CC=C(F)C(Cl)=C3)=C2C=C1OCCCN4CCOCC4)C=5C=C(O)C=C(O)C5
• Target: EGFR,Apoptosis,Akt,ERK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR,Apoptosis,Akt,ERK