EGFR-IN-109

SKU: orb2566324

Description

EGFR-IN-109 is a potent and selective EGFR inhibitor with IC50 values of 25.8 nM (WT) and 182.3 nM (T790M mutant). It induces G2/M phase cell cycle arrest and apoptosis in cancer cells, making it a valuable chemical probe for oncology research in both cellular and biochemical assays.

Research Area

Cardiovascular Research, Cell Biology, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 3019971-97-9
• MW: 264.35
• Formula: C₁₂H₁₆N₄OS
• SMILES: O=C1C=2C3=C(SC2NC(CNN)=N1)CC(C)CC3
• Target: Caspase,Bcl-2 Family,EGFR,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171364479