EGFR-IN-101

SKU: orb2566329

Description

EGFR-IN-101 (I-10) is a 2-phenylamino pyrimidine-based EGFR inhibitor, demonstrating potent activity against resistant mutants including L858R/T790M/C797S. This compound is a valuable research tool for investigating non-small cell lung cancer (NSCLC), applicable in both in vitro enzymatic assays and cellular studies using models like Ba/F3-EGFR mutant cells.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2982583-44-6
• MW: 625.81
• Formula: C₃₅H₄₇N₉O₂
• SMILES: C(N[C@H](CO)C)C=1C(=NN(C1)C2=NC(NC3=C(OC)C=C(C(C)=C3)N4CCC(CC4)N5CCN(C)CC5)=NC=C2)C6=CC=CC=C6
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171038186