Eg5-IN-1

SKU: orb1905839

Description

Eg5-IN-1 is a potent small molecule inhibitor of the mitotic kinesin Eg5, exhibiting an IC50 of 1.97 µM. It is a valuable research tool for studying cell division mechanisms and has been utilized in both in vitro and in vivo cancer research models to investigate potential anti-tumor therapies.

Research Area

Signal Transduction

Key Properties

• MW: 418.85
• Purity: 99.65% (May vary between batches)
• Formula: C₂₃H₁₆ClFN₄O
• SMILES: O=C(N/N=C/C1=CC=C(F)C=C1)C(C=C2)=CC=C2NC3=CC=NC4=CC(Cl)=CC=C43
• Target: Kinesin
• Solubility: DMSO:6.25 mg/mL (14.92 mM)

Bioactivity

• Target IC50:
  EG5:1.97 µM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Eg5, Eg5IN1, Eg5-IN-1

Compound Identifiers

PubChem CID

168476013