EF24

SKU: orb1305109

Description

EF24 (3,5-Bis[(2-fluorophenyl)methylene]-4-piperidinone) is a potent small molecule that induces apoptosis in oral squamous cell carcinoma (OSCC) by activating caspases 3/9 and inhibiting the MEK/ERK pathway. Its anti-tumor efficacy, demonstrated in both in vitro and in vivo studies, makes it a valuable research tool for investigating MAPK/ERK signaling in cancer.

Research Area

Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 342808-40-6
• MW: 311.33
• Purity: >99.99% (May vary between batches)
• Formula: C₁₉H₁₅F₂NO
• SMILES: Fc1ccccc1\C=C1/CNC\C(=C/c2ccccc2F)C1=O
• Target: Caspase,MEK,ROS,ERK,p38 MAPK,NF-κB,Apoptosis
• Solubility: DMSO:25 mg/mL (80.3 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ERK, Extracellular signal regulated kinases, EF24, EF-24, EF 24, Inhibitor, MEK1, inhibit, Caspase-3, Caspase-9, Caspase, 3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone

Compound Identifiers

PubChem CID

9885748