eEF2K degrader-1

SKU: orb2663674

Description

eEF2K degrader-1 is a potent and selective small molecule degrader of eukaryotic elongation factor 2 kinase (eEF2K). It demonstrates robust anti-tumor activity in vitro, inhibiting viability, proliferation, and migration in breast cancer cell lines such as MDA-MB-231 (IC50 = 43.71 nM), and shows efficacy in MDA-MB-231 xenograft mouse models. This compound is a valuable chemical probe for studying eEF2K's role in oncology and protein homeostasis research.

Research Area

Signal Transduction

Key Properties

• MW: 418.49
• Formula: C₂₄H₂₆N₄O₃
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Others