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Edoxaban
Catalog Number: orb1305585
| Catalog Number | orb1305585 |
|---|---|
| Category | Small Molecules |
| Description | Edoxaban |
| Purity | 99.71% |
| MW | 548.06 |
| Biological Activity | Edoxaban (Lixiana) (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K i s of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and is able to be used for stroke prevention. Edoxaban is a also weak inhibitor of thrombin and factor IXaβ (FIXa), with K i s of 6.00 μM and 41.7 μM, respectively, exhibits > 10 000-fold selectivity for FXa. Edoxaban has antithrombotic properties and is potential for thromboembolic diseases treatment [1] [2] [3]. |
| CAS Number | [480449-70-5] |
| Formula | C24H30ClN7O4S |
| SMILES | N(C(=O)C1=NC2=C(S1)CN(C)CC2)[C@H]3[C@@H](NC(C(NC4=CC=C(Cl)C=N4)=O)=O)CC[C@H](C(N(C)C)=O)C3 |
| Storage | -20°C |
| Note | For research use only |
- Item 1 of 1
Edoxaban [orb315399]
[480449-71-6]
720.259120000001
C24H30N7O4SCL.C7H8O3S
1 g, 100 mg, 250 mg, 1 ml x 10 mM (in DMSO)
