You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1305585 |
---|---|
Category | Small Molecules |
Description | Edoxaban |
CAS Number | 480449-70-5 |
Purity | 99.60% |
MW | 548.06 |
SMILES | N(C(=O)C1=NC2=C(S1)CN(C)CC2)[C@H]3[C@@H](NC(C(NC4=CC=C(Cl)C=N4)=O)=O)CC[C@H](C(N(C)C)=O)C3 |
Formula | C24H30ClN7O4S |
Biological Activity | Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K i s of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and is able to be used for stroke prevention. Edoxaban is a also weak inhibitor of thrombin and factor IXaβ (FIXa), with K i s of 6.00 μM and 41.7 μM, respectively, exhibits > 10 000-fold selectivity for FXa. Edoxaban has antithrombotic properties and is potential for thromboembolic diseases treatment [1] [2] [3]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[480449-71-6] | |
720.25912 | |
C24H30N7O4SCL.C7H8O3S |
[1229194-11-9] | |
738.2744 | |
C31H40CLN7O8S2 |
98.00% | |
1255529-24-8 | |
548.06 | |
C24H30ClN7O4S |
99.97% | |
1229194-11-9 | |
738.27 | |
C31H40ClN7O8S2 |
Filter by Rating