Edicotinib HCl

SKU: orb1739036

Description

Edicotinib (JNJ-40346527) is an orally bioavailable CSF1R/FMS tyrosine kinase inhibitor that blocks CSF1-mediated receptor activation and downstream signaling, suppressing the proliferation of CSF1R-dependent tumor cells. It has been investigated in preclinical in vitro and in vivo studies for cancers like tenosynovial giant cell tumor and glioblastoma.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1559069-92-9
• MW: 498.07
• Formula: C₂₇H₃₆ClN₅O₂
• SMILES: Cl.CC1(C)CCC(=CC1)c1nc(ccc1NC(=O)c1ncc([nH]1)C#N)C1CC(C)(C)OC(C)(C)C1
• Target: Others,c-Fms

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25230467