Edecesertib

SKU: orb1687571

Description

Edecesertib (GS-5718) is a potent, selective, and orally bioavailable IRAK-4 inhibitor used in rheumatoid arthritis research. It demonstrates anti-inflammatory activity and has been utilized in both in vitro cellular assays and in vivo animal models to study IRAK-4-mediated signaling pathways.

Research Area

Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 2408839-73-4
• MW: 435.45
• Purity: 99.94% (May vary between batches)
• Formula: C₂₂H₂₂FN₇O₂
• SMILES: N([C@@H](C#N)C)C=1C=C(C=2N3C(=CC2)C=C(C#N)C=N3)N=CC1C(NC[C@H](C(C)(C)O)F)=O
• Target: IRAK
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.58 mM);DMSO:80 mg/mL (183.72 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IRAK-4, GS5718, GS-5718, GS 5718

Compound Identifiers

PubChem CID

147817927