Echinocystic acid

SKU: orb1222140

Description

Echinocystic acid is extracted from Albizzia julibrissin Durazz.

Key Properties

• CAS Number: 510-30-5
• MW: 472.7
• Purity: >98% (HPLC)
• Formula: C₃₀H₄₈O₄
• SMILES: C1C(CC[C@@]2([C@@H](C[C@]3([C@@]4(CC[C@H]5C([C@H](CC[C@@]5([C@H]4CC=C3[C@H]12)C)O)(C)C)C)C)O)C(=O)O)(C)C
• Target: Caspase
• Solubility: DMSO : ≥ 100 mg/mL; 211.55 mM H2O : < 0.1 mg/mL

Bioactivity

• In Vivo:
  Animal model: Male adult C57BL/6 mice (8-10 week old; 18 to 22 g) injected weith Reserpine. Dosage: 5 mg/kg. Administration: Intragastrically; daily for 5 days. Result: Attenuated reserpine-induced pain/depression dyad partially through regulating the biogenic amines levels and GluN2B receptors in the hippocampus.
• In Vitro:
  Western blot analysis. Cell line: Chondrocytes. Concentration: 2.5 μM, 5 μM, 10 μM Incubation time: Pretreated 1 h and then stimulated with IL-1β for 30 min. Result: IL-1β-induced NF-κB and MAPK activation were inhibited.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase