EC-1456

SKU: orb2663334

Description

EC-1456 is a folate-conjugated microtubule inhibitor designed for targeted cancer research. It demonstrates potent antiproliferative effects in vitro and in vivo against FR-positive tumors, including drug-resistant models, making it a valuable tool for investigating targeted therapies.

Research Area

Cell Biology

Key Properties

• Target: Others,Antifolate
• CAS Number: 1602487-16-0
• MW: 2625.81
• Formula: C₁₁₀H₁₆₅N₂₃O₄₅S₃
• SMILES: [C@H](C[C@@H](N(C([C@@H](NC(=O)[C@@H]1N(C)CCCC1)[C@H](CC)C)=O)COC(CCC)=O)C(C)C)(OC(C)=O)C2=NC(C(N[C@@H](CC3=CC=C(O)C=C3)C[C@@H](C(NNC(OCCSSC[C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC([C@H](NC([C@@H](NC(CC[C@@H](NC(=O)C4=CC=C(NCC=5N=C6C(NC5)=NC(N)=NC6=O)C=C4)C(O)=O)=O)CCC(NC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O)=O)CCC(O)=O)=O)CCC(NC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O)=O)CCC(O)=O)=O)CCC(NC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O)=O)C(O)=O)=O)=O)C)=O)=CS2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172638465