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EA-C15

SKU: orb3174251

Description

EA-C15 is a potent and selective TEAD inhibitor with an IC50 value of 0.34 μM. It covalently binds to the palmitoylation site of TEAD, thereby blocking palmitoylation and transcriptional activity, inhibiting YAP-dependent cancer cell proliferation, and suppressing the transcription of YAP-TEAD downstream target genes (CTGF and CYR61). EA-C15 is applicable in cancer research.

Research Area

Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetYAP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information