E7090 succinate

SKU: orb1744692

Description

E7090 succinate is a potent and orally bioavailable small molecule inhibitor selectively targeting FGFR1-3 tyrosine kinases with sub-nanomolar IC50 values, while showing much lower activity against FGFR4. It is a valuable research tool for investigating FGFR-driven pathologies, including certain cancers, in both cellular and animal models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1879965-80-6
• MW: 1529.60
• Formula: C₇₆H₉₂N₁₀O₂₄
• SMILES: O=C(CCC(O)=O)O.O=C(C1=CC=C(C2CCN(CC2)CCO)C=C1)NC3=NC=CC(OC4=CC5=C(C=C4OCCOC)N(C(NC)=O)C=C5)=C3.O=C(CCC(O)=O)O.O=C(C6=CC=C(C7CCN(CC7)CCO)C=C6)NC8=NC=CC(OC9=CC%10=C(C=C9OCCOC)N(C(NC)=O)C=C%10)=C8.O=C(CCC(O)=O)O
• Target: Others,FGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171360913