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E3 Ligase Ligand-linker Conjugate 28

SKU: orb2566366

Description

E3 Ligase Ligand-linker Conjugate 28 is a thalidomide-based CRBN-recruiting moiety used as a key intermediate in PROTAC synthesis. This conjugate enables targeted protein degradation and is widely applied in both in vitro and in vivo research for probing disease pathways and validating novel therapeutic targets.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2229717-76-2
MW511.57
FormulaC26H33N5O6
SMILESO=C1N(C(=O)C=2C1=CC(=CC2)N3CCN(CC4CN(C(OC(C)(C)C)=O)C4)CC3)C5C(=O)NC(=O)CC5
TargetE3 Ligase Ligand-Linker Conjugates

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information