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E3 ligase Ligand-Linker Conjugate 39

SKU: orb2566364

Description

E3 ligase Ligand-Linker Conjugate 39 is a thalidomide-based Cereblon (CRBN) recruiting moiety attached to a linker. This key intermediate is widely used in PROTAC synthesis for targeted protein degradation research in both cellular and preclinical in vivo studies.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2632308-04-2
MW497.54
FormulaC25H31N5O6
SMILESO=C1N(C(=O)C=2C1=CC(=CC2)N3CC(C3)N4CCN(C(OC(C)(C)C)=O)CC4)C5C(=O)NC(=O)CC5
TargetE3 Ligase Ligand-Linker Conjugates

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information