E3 Ligase Ligand-linker Conjugate 7

SKU: orb2566356

Description

This conjugate, composed of a thalidomide-based Cereblon (CRBN) ligand and a linker, is a key intermediate for constructing PROTAC degraders. It is widely used in chemical biology and drug discovery research to facilitate targeted protein degradation studies in both cellular and preclinical models.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2758531-47-2
• MW: 538.64
• Formula: C₂₉H₃₈N₄O₆
• SMILES: O=C1N(C(=O)C=2C1=CC(=CC2)N3CCC(CN4CCC(C(OC(C)(C)C)=O)CC4)CC3)C5C(=O)NC(=O)CC5
• Target: E3 Ligase Ligand-Linker Conjugates

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168874527