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E3 ligase Ligand 49

SKU: orb2945197

Description

E3 ligase Ligand 49 serves as the E3 ubiquitin ligase-binding component of PROTAC XPO1 degrader-1. This small molecule is used in constructing PROTACs for targeted protein degradation research, applicable in both cellular and in vivo experimental models to study XPO1 function and cancer biology.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1911013-66-5
MW277.276
FormulaC13H15N3O4
SMILESO=C(NC1C(=O)NC(=O)CC1)C=2C=CC=C(N)C2OC
TargetLigands for E3 Ligase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information