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(E)-JP-2-196 TFA

SKU: orb3135773

Description

JP-2-196 (TFA) is a molecular glue handle that binds in vitro with E3 ubiquitin ligases [RNF126, LRSAM1, RNF40, MID2, and RNF14]. It is applicable in the synthesis of molecular glue degraders.

Research Area

Immunology & Inflammation; Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3065021-33-9
MW388.34
FormulaC17H19F3N2O5
SMILESC(C(O)=O)(F)(F)F.C(/C=C/C(=O)N1CCNCC1)(=O)C2=CC=C(OC)C=C2
TargetE3 Ligase Ligand-Linker Conjugates

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information