(E)-AG 556

SKU: orb1306176

Description

AG 556 is a selective epidermal growth factor receptor (EGFR) inhibitor that also suppresses lipopolysaccharide (LPS)-induced TNF-α release. This compound is utilized in research areas such as inflammation and oncology, supporting both in vitro cellular studies and in vivo experimental models to investigate EGFR signaling and cytokine regulation.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 133550-41-1
• MW: 336.38
• Purity: 99.93% (May vary between batches)
• Formula: C₂₀H₂₀N₂O₃
• SMILES: C(=C(/C(NCCCCC1=CC=CC=C1)=O)\C#N)\C2=CC(O)=C(O)C=C2
• Target: EGFR
• Solubility: DMSO:50 mg/mL (148.64 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(E)AG 556, (E)-AG 556, (E) AG 556, (E)-Tyrphostin AG 556, AG556, AG-556, AG 556, inhibit, EGFR, ErbB-1, Epidermal growth factor receptor, Inhibitor, HER1

Compound Identifiers

PubChem CID

5328775