E-6837

SKU: orb3210649

Description

E-6837 is a selective, orally active ligand for the 5-HT6 receptor. It acts as a partial agonist on the presumed silent rat 5-HT6 receptor by monitoring the cAMP signaling pathway, while demonstrating full agonist activity on the constitutively activated human 5-HT6 receptor. E-6837 reduces food intake, decreases fat mass and body weight, and improves blood glucose control. This compound is relevant for research studies related to obesity.

Key Properties

• CAS Number: 528859-61-2
• MW: 427.95
• Formula: C₂₂H₂₂ClN₃O₂S
• SMILES: O=S(=O)(NC=1C=CC=2NC=C(C2C1)CCN(C)C)C=3C=CC=4C(Cl)=CC=CC4C3
• Target: 5-HT Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

5-HT Receptor