(E)-6-O-p-Coumaroyl scandoside methyl ester

SKU: orb1680120

Description

(E)-6-O-p-Coumaroyl scandoside methyl ester is a bioactive iridoid glycoside isolated from Oldenlandia diffusa. It serves as a valuable research compound for biochemical assays and medicinal chemistry, with studies indicating potential anti-inflammatory and anti-tumor activities in cellular models.

Key Properties

• CAS Number: 83946-90-1
• MW: 550.51
• Purity: 99.92% (May vary between batches)
• Formula: C₂₆H₃₀O₁₃
• SMILES: [H][C@]12[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C(C(=O)OC)[C@@]1([H])[C@H](OC(=O)C=Cc1ccc(O)cc1)C=C2CO
• Target: Others

Bioactivity

• In Vitro:
  Baihuasheshecao (Hedyotis diffusa), a Chinese herb for cancer treatment, is frequently adulterated by a related species Hedyotis corymbosa. Chemical analyses by TLC and HPLC were used to authenticate H. diffusa and H. corymbosa. Two marker compounds were identified exclusively in H. diffusa: (E)-6-O-p-Coumaroyl scandoside methyl ester and 10(S)-hydroxypheophytin a. Both compounds showed moderate anti-proliferation effect on PC3 human androgen-independent prostate cancer cells, while 10(S)-hydroxypheophytin a also showed strong anti-proliferation effect on LNCaP human androgen-sensitive prostate cancer cells. Accordingly, these bioactive marker compounds could be applied to verify the authenticity and assess the quality of Baihuasheshecao.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

6-O-(p-coumaroyl)scandoside methyl ester, 6-O-E-pcoumaroyl scandoside methyl ester, (E)6O(pcoumaroyl)scandoside methyl ester, (E)-6-O-(p-coumaroyl)scandoside methyl ester, (E) 6 O (p coumaroyl)scandoside methyl ester

Compound Identifiers

PubChem CID

162935981