(E)-3,4,5-Trimethoxycinnamic acid

SKU: orb1297136

Description

O-Methylsinapic acid, also known as (E)-3,4,5-Trimethoxycinnamic acid, is a natural compound isolated from Notopterygium incisum. It serves as a research standard and has been investigated in vitro for its potential anti-inflammatory and antioxidant properties in biochemical studies.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 20329-98-0
• MW: 238.2366
• Purity: 99.83% (May vary between batches)
• Formula: C₁₂H₁₄O₅
• SMILES: COC1=CC(=CC(OC)=C1OC)\C=C\C(O)=O
• Target: Others,GABA Receptor,5-HT Receptor
• Solubility: DMSO:60 mg/mL (251.85 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.39 mM)

Bioactivity

• Target IC50:
  5-HT2C receptor:2.5 μM|5-HT2A receptor:>10 μM|5-HT6 receptor:>10 μM|5-HT7 receptor:>10 μM|5-HT1A receptor:7.6 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

antidepressant, anticonvulsant, anti-seizure, 5-hydroxytryptamine Receptor, 3,4,5-Trimethoxyphenylacrylic acid, 3,4,5-Trimethoxy-trans-cinnamic acid, 3,4,5-Trimethoxycinnamic acid, (E) 3,4,5 Trimethoxycinnamic acid, (E)3,4,5Trimethoxycinnamic acid, 5-HT Receptor, headache, epilepsy, GABA Receptor, Gamma-aminobutyric acid Receptor, O-Methylsinapic acid, Inhibitor, inhibit, TMCA, Polygalaceae, sedative, Serotonin, Serotonin Receptor, γ-Aminobutyric acid Receptor

Compound Identifiers

PubChem CID

735755