(E)-2-Decenoic acid

SKU: orb1299912

Description

(E)-2-Decenoic acid is a trans-configuration unsaturated fatty acid naturally present in honeybee royal jelly. It serves as a research tool in studies of aging, antimicrobial activity, and cell signaling, with applications in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 334-49-6
• MW: 170.25
• Purity: 98.00%
• Formula: C₁₀H₁₈O₂
• SMILES: CCCCCCC\C=C\C(O)=O
• Target: Others
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (23.49 mM);DMSO:100 mg/mL (587.37 mM)

Bioactivity

• In Vitro:
  Trans-2-decenoic acid does not inhibit AI-2-specific signaling, but rathe the luciferase reaction used for its detection. A potential biological role of trans-2-decenoic acid was then discovered. It is able to suppres the transition from yeast to hyphal morphology in the opportunistic human pathogen andida albicans at concentration that do not affect growth the expression of HWP1, a hyphal-specific signature gene of C. albicans, is abolished by trans-2-decenoic acid. trans-2-Decenoic acid is structurally similar to the diffusible signal factor (DSF) family of interkingdom-signaling molecules and in the first member of this family from a Gram-positive organism (Streptococcus DSF, SDSF). SDSF activity was also found in S. mitis, S. oralis, and S. sanguinis, but not in Other oral bacteria. SDSF could be relevant in shaping multispecies andida bacteria biofilms in the human bod.

Storage & Handling

• Storage: Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, 2-Decenoic acid, (E) 2 Decenoic acid, (E)2Decenoic acid, trans-2-Decenoic acid

Compound Identifiers

PubChem CID

5282724