DYRKs-IN-1

SKU: orb1709813

Description

DYRKs-IN-1 is a potent and selective small molecule inhibitor of DYRK1A and DYRK1B kinases, exhibiting IC50 values of 5 nM and 9 nM, respectively. It demonstrates antitumor properties and is a valuable chemical probe for studying DYRK family functions in cancer biology, cell cycle regulation, and neurodegenerative disease research in both cellular and animal models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1387090-01-8
• MW: 588.06
• Formula: C₃₀H₃₀ClN₇O₄
• SMILES: O=C1N=C2NC(N3CC4OC(C3)CC4)=NC=C2C=C1C(NC5=CC(C(NC(CCN)C6=CC=CC=C6)=O)=CC=C5Cl)=O
• Target: DYRK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

70370554