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Dynamin IN-2

SKU: orb1819236

Description

Dynamin IN-2 (compound 43) is a potent, cell-permeable dynamin inhibitor derived from Wiskostatin, with an IC50 of 1.0 µM against dynamin I GTPase. It effectively blocks clathrin-mediated endocytosis (IC50= 9.5 µM) and is a valuable chemical tool for studying endocytic pathways in cellular and biochemical assays.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number1345853-49-7
MW364.87
Purity99.37%
FormulaC22H21ClN2O
SMILESC(C(CNCC1=CC=C(Cl)C=C1)O)N2C=3C(C=4C2=CC=CC4)=CC=CC3
TargetDynamin
SolubilityDMSO:60 mg/mL (164.44 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Dynamin IN-2, Dynamin, DynaminIN2

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Key Properties

No computed properties available.

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Dynamin IN-2 (orb1819236)

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Available Sizes

Select a size below

1 mg
$ 190.00
5 mg
$ 390.00
1 ml x 10 mM (in DMSO)
$ 400.00
10 mg
$ 510.00
25 mg
$ 750.00
50 mg
$ 990.00
100 mg
$ 1,300.00
200 mg
$ 1,720.00
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